Formaldehyde uye glutaraldehydeese ari maviri emakemikari anoshandiswa seanoyambuka maajenti mukushandisa kwakasiyana, kunyanya muminda yebiology, chemistry, uye zvinhu sainzi.Kunyange ivo vachishandira zvinangwa zvakafanana mukuyambuka biomolecules uye kuchengetedza zvipenyu zvipenyu, vane akasiyana makemikari zvimiro, reactivity, chepfu, uye mashandisirwo.
Zvakafanana:
Crosslinking Agents: Zvese formaldehyde uyeglutaraldehyde inonzi aldehydes, zvinoreva kuti vane boka re carbonyl (-CHO) pamagumo ekugadzirwa kwavo kwema molecular.Basa ravo rekutanga ndere kuumba covalent zvisungo pakati peanoshanda mapoka emabiomolecules, zvichikonzera kuyambuka.Crosslinking yakakosha pakudzikamisa chimiro chebiological samples, zvichiita kuti dziwedzere kusimba uye dzinopesana nekudzikira.
Biomedical Applications: Zvose formaldehyde uye glutaraldehyde zvinowana kushandiswa kwakakosha mumunda webiomedical.Ivo vanowanzo shandiswa kugadzirisa matishu uye kuchengetedza mune histology uye pathology zvidzidzo.Iwo ma-crosslinked tissues anochengetedza kutendeseka kwawo uye anogona kuenderera mberi nekugadziriswa kune akasiyana ekuongorora uye kuongororwa zvinangwa.
Kudzora kweMicrobial: Maajenti ese ari maviri ane antimicrobial properties, zvichiita kuti ave akakosha mukuuraya utachiona nekuita sterilization maitiro.Ivo vanogona kudzima bhakitiriya, mavhairasi, uye fungi, kuderedza njodzi yekusvibiswa mumarabhoritari marongero uye michina yekurapa.
Industrial Applications: Zvose formaldehyde uyeglutaraldehydeanoshandiswa mumhando dzakasiyana dzemaindasitiri ekushandisa.Ivo vanoshandirwa mukugadzira zvinonamira, resin, uye mapolymers, pamwe nemuindasitiri yematehwe uye machira.
Misiyano:
Kemikari Yakarongeka: Musiyano mukuru pakati pe formaldehyde uye glutaraldehyde uri mune yavo molecular zvimiro.Formaldehyde (CH2O) ndiyo aldehyde yakapfava, inoumbwa neatomu kabhoni imwe, maatomu maviri ehydrogen, uye atomu imwe yeokisijeni.Glutaraldehyde (C5H8O2), kune rumwe rutivi, ikanyanya kuoma aliphatic aldehyde, inosanganisira mashanu maatomu ecarbon, masere maatomu ehydrogen, uye maviri maatomu eokisijeni.
Reactivity: Glutaraldehyde inowanzoita reactivity pane formaldehyde nekuda kweiyo refu kabhoni ketani.Kuvepo kwemaatomu ekabhoni mashanu muglutaraldehyde kunoibvumira kubhuroka madaro marefu pakati pemapoka anoshanda pamabiomolecules, zvichitungamira kukurumidza uye kwakanyatso kuyambuka.
Crosslinking Efficiency: Nekuda kwepamusoro reactivity yayo, glutaraldehyde inowanzo shanda pakuyambuka ma biomolecules makuru, senge mapuroteni nema enzymes.Formaldehyde, ichiri kukwanisa kuyambuka, inogona kuda nguva yakawanda kana yakakwira kuti iwane mibairo inofananidzwa nemamorekuru makuru.
Toxicity: Glutaraldehyde inozivikanwa kuva ine chepfu kupfuura formaldehyde.Kugara kwenguva refu kana kwakakosha kuratidzwa kune glutaraldehyde kunogona kukonzera ganda uye kushatirwa kwekufema, uye inonzi sensitizer, zvichireva kuti inogona kutungamira kune allergic reaction mune vamwe vanhu.Kusiyana neizvi, formaldehyde icarcinogen inozivikanwa uye inoisa njodzi pautano, kunyanya kana ikafemerwa kana kubata ganda.
Zvishandiso: Kunyangwe makemikari ese ari maviri achishandiswa mukugadzirisa matishu, anowanzo kusarudzwa nekuda kwezvinangwa zvakasiyana.Formaldehyde inowanzo shandiswa kuita zvechinyakare histological application uye kuomesa, nepo glutaraldehyde inonyanya kukodzera kuchengetedza cellular zvimiro uye antigenic nzvimbo muelectron microscopy uye immunohistochemical zvidzidzo.
Kugadzikana: Formaldehyde inonyanya kushanduka uye inoputika nekukurumidza kupfuura glutaraldehyde.Ichi chivakwa chinogona kukanganisa kubata uye kuchengetedza zvinodiwa zve crosslinking agents.
Muchidimbu, formaldehyde uye glutaraldehyde vanogovana hunhu hwakafanana sevanoyambuka, asi ivo vanosiyana zvakanyanya mumakemikari avo maumbirwo, reactivity, chepfu, uye mashandisirwo.Kunzwisisa kwakaringana kwemisiyano iyi kwakakosha pakusarudza mumiriri akakodzera wekubatanidza kune zvinangwa chaizvo uye kuve nechokwadi chekushandiswa kwakachengeteka uye kunobudirira mumamiriro akasiyana esainzi, ekurapa, uye maindasitiri.
Nguva yekutumira: Jul-28-2023