Chlorphenesin

Chlorphenesin(104-29-0), zita remakemikari ndi3-(4-chlorophenoxy)propane-1,2-diol, inowanzogadzirwa nekuita kwep-chlorophenol nepropylene oxide kana epichlorohydrin. Imushonga unorwisa mabhakitiriya uye unorwisa mabhakitiriya, une simba rekuuraya mabhakitiriya eGram-positive, mabhakitiriya eGram-negative, mbiriso uye molds. Yakatenderwa kushandiswa muzvizoro nenyika dzakawanda nenzvimbo dzakadai seEurope, United States, Japan, neChina. Muganho wekushandiswa wakatenderwa nemitemo nemimwe mizhinji yenyika i0.3%.
ChlorphenesinPakutanga yakanga isingashandiswi semushonga unochengetedza, asi semushonga unodzvinyirira immune une chekuita neantigen unodzivisa kuburitswa kwehistamine inofambiswa neIgE muindasitiri yemishonga. Zvichitaurwa zviri nyore, inoderedza allergy. Kare muna 1967, indasitiri yemishonga yakanga yadzidza nezvekushandiswa kwechlorphenesin nepenicillin kudzivirira allergy inokonzerwa nepenicillin. Chlorphenesin yakazowanikwa nevaFrance nekuda kwemhedzisiro yayo yekuuraya utachiona uye bacteriostatic uye yakashandisirwa patents dzine chekuita nayo.
1. Chlorphenesin inozorodza tsandanyama here?
Mushumo wekuongorora wakataura zvakajeka kuti: chinhu chinogadzirwa ne chlorphenesin hachina simba rekuderedza tsandanyama. Uye chataurwa kakawanda mumushumo wacho: Kunyangwe chidimbu chechirungu chechinhu chinogadzirwa nemishonga chinonzi chlorphenesin nechinogadzirwa ne chlorphenesin chiri Chlorphenesin, zviviri izvi hazvifanirwe kuvhiringidzwa.
2. Chlorphenesin inotsamwisa ganda here?
Kungave kwevanhu kana mhuka, chlorphenesin haina ganda rinotsamwisa panguva yakatarwa, uye haisi chinhu chinodzivirira ganda kana kuti chinokonzeresa kutsva. Kune zvinyorwa zvina kana zvishanu chete nezvemishumo yekuti chlorphenesin inokonzera kuzvimba kweganda. Uye kune zviitiko zvishoma apo chlorphenesin inoshandiswa iri 0.5% kusvika 1%, ichipfuura zvakanyanya huwandu hunoshandiswa muzvizoro. Mune zvimwe zviitiko zvakawanda, zvakangotaurwa chete kuti chlorphenesin yaive mufomula, uye pakanga pasina humbowo hwakananga hwekuti chlorphenesin yakakonzera dermatitis. Tichifunga nezvekushandiswa kukuru kwechlorphenesin muzvizoro, mukana uyu hauna kukosha.
3. Ko chlorphenesin ichapinda muropa here?
Kuedzwa kwemhuka kwakaratidza kuti imwe chlorphenesin inopinda muropa mushure mekunge yabata ganda. Chlorphenesin yakawanda inonyudzwa inozogadziriswa muweti, uye yese inoburitswa mumuviri mukati memaawa makumi mapfumbamwe nematanhatu. Asi maitiro ese haazove nemigumisiro ine chepfu.
4. Ko Chlorphenescine inoderedza dziviriro yemuviri here?
Hazvizoitiki. Chlorphenesin mushonga unodzvinyirira immune system une chekuita neantigen. Chekutanga, chlorphenesin inongoshanda basa rakakosha kana ikabatanidzwa neantigen yakatarwa, uye haideredzi dziviriro yemuviri, uye haiwedzere huwandu hwehutachiona hwezvirwere. Chechipiri, mushure mekumira kushandisa, simba rekudzivirira immune system reantigen yakatarwa richapera, uye hapazovi nemhedzisiro inogara iripo.
5. Ndeipi mhedziso yekupedzisira yekuongorora kuchengetedzeka?
Zvichienderana nemashandisirwo aripo uye huwandu hwekushandiswa muUnited States (wash-off 0.32%, resident type 0.30%), FDA inotenda kutichlorphenesinyakachengeteka semushonga wekuchengetedza runako.