Chlorphenesin

Chlorphenesin(104-29-0), kemikari zita 3-(4-chlorophenoxy) propane-1,2-diol, inowanzogadzirwa nekuita kwep-chlorophenol ine propylene oxide kana epichlorohydrin.Iyo yakakura-spectrum antiseptic uye antibacterial agent, ine antiseptic effect paGram-positive bacteria, Gram-negative bacteria, yeasts uye molds.Yakatenderwa kuti ishandiswe muzvizoro nenyika zhinji nematunhu akadai seEurope, United States, Japan, neChina.Muganho wekushandisa unobvumidzwa nemitemo yakawanda yenyika uye mirau ndeye 0.3%.
Chlorphenesinyakanga isati yashandiswa sekuchengetedza, asi se antigen-yakabatana immunosuppressant iyo inhibits IgE-mediated histamine kusunungurwa muindasitiri yemishonga.Zvichitaurwa zviri nyore, inorwisa-allergic.Kare muna 1967, indasitiri yemishonga yakanga yadzidza kushandiswa kwechlorphenesin nepenicillin kurambidza kusawirirana kunokonzerwa nepenicillin.Yakanga isiri kusvika 1997 apo chlorphenesin yakawanikwa nevaFrench nekuda kweiyo antiseptic uye bacteriostatic mhedzisiro uye yakashandisirwa patents inoenderana.
1. Ko chlorphenesin inozorodza tsandanyama here?
Chirevo chekuongorora chakaratidza zvakajeka: iyo cosmetic ingredient chlorphenesin haina mhasuru-yekudzoreredza maitiro.Uye inotaurwa kakawanda mumushumo: Kunyangwe chidimbu cheChirungu chemishonga yemishonga chlorphenesin uye cosmetic ingredient chlorphenesin zviri zviviri Chlorphenesin, izvo zviviri hazvifanirwe kuvhiringidzika.
2. Ko chlorphenesin inoshungurudza ganda here?
Ingave yevanhu kana mhuka, chlorphenesin haina kushatirwa kweganda panguva yakajairika, uye haisi sensitizer yeganda kana photosensitizer.Pane zvinyorwa zvina kana zvishanu chete nezve mishumo yechlorphenesin inokonzera kuzvimba kweganda.Uye kune mashoma mashoma apo chlorphenesin yakashandiswa iri 0.5% kusvika 1%, inodarika zvakanyanya kusungwa kunoshandiswa muzvizora.Mune zvimwe zviitiko zvakati wandei, zvakangotaurwa kuti chlorphenesin yaive mufomula, uye pakanga pasina humbowo hwakananga hwekuti chlorphenesin yakakonzera dermatitis.Tichifunga nezvehukuru hwekushandisa hwaro hwechlorphenesin muzvizoro, mukana uyu hauna basa.
3. Ko chlorphenesin inopinda muropa here?
Kuedza kwemhuka kwakaratidza kuti imwe chlorphenesin ichapinda muropa mushure mekunge yasangana neganda.Yakawanda yechlorphenesin yakabatwa ichave yakagadziriswa muweti, uye yese ichaburitswa kubva mumuviri mukati memaawa makumi mapfumbamwe nematanhatu.Asi maitiro ese haaburitse chero chepfu mhedzisiro.
4. Ko Chlorphenescine ichaderedza kudzivirirwa kwezvirwere here?
Handingadaro.Chlorphenesin inogadziriswa antigen-yakabatana immunosuppressant.Chekutanga pane zvese, chlorphenesin inongotora basa rakakodzera kana yasanganiswa neantigen yakatarwa, uye haideredze kusadzivirirwa kwemuviri wega, uye haina kuwedzera huwandu hwehutachiona hwezvirwere.Chechipiri, mushure mekupera kwekushandisa, iyo immunosuppressive mhedzisiro yeyakatarwa antigen ichanyangarika, uye hapazovi nemhedzisiro inoenderera.
5. Ndeipi mhedziso yekupedzisira yekuongororwa kwekuchengetedza?
Zvichienderana nezviripo mashandisirwo uye mashandisiro ekushandisa muUnited States (wash-off 0.32%, mugari rudzi 0.30%), iyo FDA inotenda izvozvo.chlorphenesinyakachengeteka sechinhu chinochengetedza zvizorwa.