Seyakazara yakatwasuka-cheni aliphatic dibasic aldehyde, glutaraldehyde imvura isina ruvara inoonekera ine kunhuhwirira kunokatyamadza uye yakanakisa kuuraya mabhakitiriya ekubereka, mavhairasi, mycobacteria, pathogenic mold uye bhakitiriya bhakitiriya, uye isiri-oxidizing yakakura-spectrum bactericide.Glutaraldehyde mushonga unouraya utachiona hwakasiyana siyana uye inokurudzirwa neWorld Health Organisation semushonga wekuuraya hutachiona hwehepatitis.
Glutaraldehyde 25%ine zvinokurudzira nekurapa zvinokonzeresa paganda remunhu uye mucous membranes uye zvinogona kukonzera allergies, saka haifanirwe kushandiswa kuuraya hutachiona hwemhepo nemidziyo yechikafu.Pamusoro pezvo, glutaraldehyde haifanirwe kushandiswa kuuraya hutachiona uye sterilization yemidziyo yekurapa tubular, tsono dzejekiseni, sutures yekuvhiya uye tambo dzedonje.
Glutaraldehyde inowanzoshandiswa semishonga inouraya utachiona muindasitiri yezvokurapa uye vashandisi vanogona kunge vaine mibvunzo ine chekuita nenyaya dzehunyanzvi, saka Springchem pano inopa mapoinzi makuru nezve glutaraldehyde yako.
Akushandiswa kwe glutaraldehyde
Glutaraldehyde inoshandiswa sechinhu chinotonhora sterilant kuuraya utachiona zvinopisa kupisa, senge endoscopes uye dialysis michina.Inoshandiswa semushonga wepamusoro-soro kune izvo zviridzwa zvekuvhiya izvo zvisingakwanisi kupisa sterilized.
Glutaraldehyde inoshandiswa kune akati wandei kunyorera munzvimbo dzehutano:
● Chigadziro chetishu mumarabhoritari ezvirwere
● Mushonga wekuuraya utachiona uye kuchenesa nzvimbo nemidziyo
● Mushonga wekuomesera wakashandiswa kugadzira X-rays
● Nokuda kwekugadzirira kwegrafts
Kuperazuva re glutaraldehyde uye nzira yekuziva kupera kwayo
Pakupisa kwekamuri uye pasi pemamiriro ekuve kure nechiedza uye chisimbiso chekuchengetedza, zuva rekupera kwe glutaraldehyde harifaniri kunge riri pasi pemakore maviri, uye iyo inoshandiswa inoshandiswa ye glutaraldehyde inofanira kuva inenge 2.0% mukati mekupera kwemazuva.
Pane tembiricha yemumba, mushure mekuwedzera rust inhibitor uye pH adjuster, glutaraldehyde inoshandiswa pakurapa mudziyo kunyudzwa disinfection kana sterilization, uye inogona kushandiswa kwemazuva gumi nemana anoenderera.Iyo glutaraldehyde yemukati inofanirwa kunge iri 1.8% panguva yekushandiswa.
Kunyudzwadutachionanziraine glutaraldehyde
Soka zviridzwa zvakacheneswa mu 2.0% ~ 2.5% glutaraldehyde disinfection solution kuti uzvinyure zvachose, wobva wavhara mudziyo wekuuraya utachiona patembiricha yekamuri kwemaminetsi makumi matanhatu, wogeza nemvura isina utachiona usati washandisa.
Iyo yakacheneswa uye yakaomeswa yekuongorora uye yekurapa zviridzwa, zvishandiso uye zvinyorwa zvinoiswa mu 2% alkaline glutaraldehyde mhinduro yakanyudzwa zvachose, uye mabhuru emhepo ari pamusoro pezviridzwa anofanirwa kubviswa nemudziyo wakavharwa pakudziya kwe20 ~ 25 ℃.Iyo disinfection inoshanda kusvika panguva yakatarwa yemirairo yechigadzirwa.
Zvinodiwa zve disinfection ye endoscopes ne glutaraldehyde
1. High level disinfection uye sterilization parameters
● Kuisa pfungwa: ≥2% (alkaline)
● Nguva: bronchoscopy disinfection kunyudzwa nguva ≥ 20min;mamwe endoscopes disinfection ≥ 10min;endoscopic kunyudzwa kwevarwere vane mycobacterium tuberculosis, mamwe mycobacteria nezvimwe zvirwere zvakakosha ≥ 45min;sterilization ≥ 10h
2. Shandisa nzira
● Endoscope yekuchenesa uye disinfection muchina
● Manual operation: disinfectant inofanira kuzadzwa nepombi imwe neimwe uye yakanyoroveswa kuti iite disinfectant
3. Chengetedzo
Glutaraldehyde 25%is allergenic uye inogumbura ganda, maziso nekufema, uye inogona kukonzera dermatitis, conjunctivitis, kuzvimba kwemhino uye asthma yebasa, saka inofanirwa kushandiswa mukuchenesa endoscope uye disinfection muchina.
Kuchengetedza ne glutaraldehyde
Glutaraldehyde inogumbura ganda uye mucous membranes uye ine chepfu kuvanhu, uye glutaraldehyde mhinduro inogona kukonzera kukuvadza kwakanyanya kumaziso.Nokudaro, inofanira kugadzirirwa uye kushandiswa munzvimbo ine mhepo yakanaka, kuchengetedzwa kwemunhu kunofanira kugadzirirwa zvakanaka, zvakadai sekupfeka masikisi ekudzivirira, magirovhosi ekudzivirira uye magirazi ekudzivirira.Kana ikabatwa zvisina kufanira, inofanira kugezwa nokukurumidza uye nguva dzose nemvura, uye kurapwa kwokukurumidza kunofanira kutsvakwa kana maziso akuvara.
Inofanirwa kushandiswa munzvimbo inofefetera zvakanaka, uye kana zvichidikanwa, nzvimbo yacho inofanira kunge iine michina yekupedza simba.Kana huwandu hwe glutaraldehyde mumhepo panzvimbo yekushandiswa hwakanyanyisa, zvinokurudzirwa kuve nemidziyo yekufema inozvimiririra (positive pressure inodzivirira mask).Midziyo inoshandiswa pakunyorovesa midziyo inofanira kunge yakachena, yakavharwa uye nekuuraya utachiona isati yashandiswa.
Monitoring frequency ye glutaraldehyde concentration
Iko kunoshanda kwe glutaraldehyde kunogona kutariswa nemakemikari test strips.
Mukuita kwekuenderera mberi kwekushandisa, kutarisa kwezuva nezuva kunofanira kusimbiswa kuti inzwisise kuchinja kwayo kwekugadzirisa, uye haifaniri kushandiswa kana kusungirirwa kwayo kunowanikwa pasi pehuwandu hunodiwa.
Izvo zvinofanirwa kuve nechokwadi chekuti kuunganidzwa kwe glutaraldehyde mukushandiswa kunosangana nezvinodiwa zvechigadzirwa bhuku.
Unofaniraglutaraldehyde inofanira kushandiswa isati yashandiswa?
Iyo aqueous solution ye glutaraldehyde ine acidic uye kazhinji haigone kuuraya mabudding spores mune acidic state.Izvo chete kana mhinduro "yakagadziriswa" nealkalinity kune pH kukosha kwe7.5-8.5 iyo inogona kuuraya spores.Kana yangoitwa, mhinduro idzi dzine hupenyu hwesherufu hwemazuva gumi nemana.Pa alkaline pH mazinga, glutaraldehyde mamorekuru anowanzoita polymerize.Iyo polymerization yeglutaraldehyde inoguma nekuvharwa kweiyo inoshanda saiti aldehyde boka reiyo glutaraldehyde molecule inokonzera kuuraya budding spores, uye nekudaro bactericidal mhedzisiro inoderedzwa.
Zvinhu zvinokanganisa sterilization ye glutaraldehyde
1. Kuisa pfungwa uye nguva yekuita
Iyo bactericidal mhedzisiro ichawedzerwa nekuwedzera kwekutarisa uye nekuwedzera kwenguva yekuita.Nekudaro, mhinduro yeglutaraldehyde ine chikamu chemashoma isingasviki 2% haigone kuwana yakavimbika bactericidal mhedzisiro pane mabhakitiriya spores, zvisinei kuti ungawedzera sei nguva yebhakitiriya.Naizvozvo, zvinodikanwa kushandisa glutaraldehyde solution ine chikamu chikuru chinodarika 2% kuuraya mabhakitiriya spores.
2. Solution acidity uye alkalinity
Iyo bactericidal mhedzisiro yeasidhi glutaraldehyde yakadzikira zvakanyanya kupfuura yealkaline glutaraldehyde, asi mutsauko uchadzikira zvishoma nezvishoma nekuwedzera tembiricha.Muchikamu chepH 4.0-9.0, iyo bactericidal effect inowedzera nekuwedzera pH;iyo yakasimba bactericidal effect inoonekwa pa pH 7.5-8.5;pa pH> 9, glutaraldehyde inokurumidza polymerize uye bactericidal effect inokurumidza kurasika.
3. Tembiricha
Iyo inewo bactericidal effect pakudzika kwakadzika.Iyo bactericidal mhedzisiro ye glutaraldehyde inowedzera nekupisa, uye tembiricha yayo coefficient (Q10) ndeye 1.5 kusvika 4.0 pa20-60 ℃.
4. Organic matter
Organic nyaya inoita kuti hutachiona huve husina simba, asi mhedzisiro ye organic matter pa bactericidal effect ye glutaraldehyde idiki pane yemamwe ma disinfectants.20% yemhuru serum uye 1% ropa rose harina zvazvinoita pahutachiona hwe2% glutaraldehyde.
5. Synergistic effect ye nonionic surfactants uye zvimwe physicochemical factor
Polyoxyethylene fatty alcohol ether is nonionic surfactant, uye kugadzikana uye bactericidal mhedzisiro inovandudzwa zvakanyanya nekuwedzera 0.25% polyoxyethylene mafuta edoro ether kune glutaraldehyde mhinduro yakagadzirwa neyakasimbiswa acid-base glutaraldehyde.Ultrasound, kure infrared mwaranzi uye glutaraldehyde ine synergistic sterilization maitiro.
Springchem, yeChina yepamusoro gumi yekugadzira glutaraldehyde, inopa glutaraldehyde 25% uye 50% yeindasitiri, marabhoritari, zvekurima, zvekurapa, uye zvimwe zvinangwa zvemba, kunyanya kuuraya hutachiona uye sterilization yenzvimbo nemidziyo.Kuti uwane rumwe ruzivo, ingo taura nesu.
Nguva yekutumira: Aug-16-2022