Ko phenoxyethanol inokuvadza paganda here?

Chiiphenoxyethanol?
Phenoxyethanol is a glycol ether inoumbwa nekubatanidza phenolic mapoka ne ethanol, uye inoratidzika semafuta kana mucilage mumamiriro ayo emvura.Iyo yakajairika kuchengetedza mune zvizorwa, uye inogona kuwanikwa mune zvese kubva kumeso ma creams kusvika kune lotions.
Phenoxyethanol inobudirira kuchengetedza kwayo kwete kuburikidza neantioxidant asi kuburikidza neayo anti-microbial basa, iyo inhibits uye kunyange kubvisa mahombe emadhora e gram-positive uye negative microorganisms.Iyo inewo yakakosha inhibitory effect pamhando dzakasiyana-siyana dzebhakitiriya dzakadai seE. coli uye Staphylococcus aureus.
Ko phenoxyethanol inokuvadza paganda here?
Phenoxyethanol inogona kuuraya kana ikanwiwa mumadosi makuru.Nekudaro, topical application yephenoxyethanolpazvikamu zvisingasviki 1.0% ichiri mukati mehutano hwakachengeteka.
Isu takambokurukura kana ethanol yakagadziriswa kuacetaldehyde yakawanda paganda uye kuti inobatwa muhuwandu hwakawanda neganda.Zvose izvi zvakakoshawo kune phenoxyethanol.Kune ganda rine chivhariso chakasimba, phenoxyethanol imwe yeinokurumidza kushatisa glycol ethers.Kana iyo metabolic pathway ye phenoxyethanol yakafanana neye ethanol, danho rinotevera nderekuumbwa kweacetaldehyde isina kugadzikana, inoteverwa ne phenoxyacetic acid uye zvimwe mahara radicals.
Usanetseka zvakadaro!Patakakurukura retinol kare, takataurawo nezve enzyme system ine chekuita nemetabolism yephenoxyethanol, uye kuti idzi nzira dzekushandura dzinoitika pasi pe stratum corneum.Saka isu tinofanirwa kuziva kuti yakawanda sei phenoxyethanol inotorwa transdermally.Mune imwe tsvakurudzo yakaedza kubatwa kwemvura-based sealant ine phenoxyethanol uye zvimwe zvinorwisa-microbial ingredients, ganda renguruve (iro rinenge riri pedyo rinokwanisa kupinza vanhu) raizotora 2% phenoxyethanol, iyo yakawedzerawo kusvika 1.4% chete mushure memaawa matanhatu, uye 11.3% mushure memaawa makumi maviri nemasere.
Zvidzidzo izvi zvinoratidza kuti kutorwa uye kushandurwa kwephenoxyethanolpazvikamu zvisingasviki 1% haina kukwirira zvakakwana kuti ibudise mishonga inokuvadza yemetabolites.Migumisiro yakafanana yakawanikwawo muzvidzidzo vachishandisa vacheche vachangoberekwa pasi pemavhiki e27.Chidzidzo chacho chakati, "Aqueousphenoxyethanolhaikonzeri kukuvara kwakanyanya kweganda kana ichienzaniswa ne ethanol-based preservatives.Phenoxyethanol inonyura muganda revacheche vachangoberekwa, asi haigadziri chigadzirwa che oxidation phenoxyacetic acid muhuwandu hunokosha." Mhedzisiro iyi inoratidzawo kuti phenoxyethanol ine mwero wepamusoro wemetabolism muganda uye haikonzeri kukuvara kwakanyanya. zvibate, unotyei?
Ndiani ari nani, phenoxyethanol kana doro?
Kunyangwe phenoxyethanol yakagadziriswa nekukurumidza kupfuura ethanol, iyo yakanyanya kuganhurirwa yekumisikidza kune topical application yakadzikira pa1%, saka haisi kuenzanisa kwakanaka.Sezvo iyo stratum corneum ichidzivirira mazhinji emamorekuru kubva pakubatwa, iwo emahara radicals anogadzirwa neaya maviri ari mashoma pane ayo anogadzirwa neavo oxidation maitiro zuva rega rega!Uyezve, nokuti phenoxyethanol ine phenolic mapoka muchimiro chemafuta, inoputika uye inomesa zvishoma nezvishoma.
Summary
Phenoxyethanol chinhu chinowanzo chengetedza chinoshandiswa muzvizoro.Yakachengeteka uye inoshanda, uye yechipiri chete kune parabens maererano nekushandiswa.Kunyangwe ini ndichifunga kuti parabens zvakare yakachengeteka, kana iwe uchitsvaga zvigadzirwa zvisina parabens, phenoxyethanol isarudzo yakanaka!