Yaimbozivikanwa se "kuchenesa goridhe", uye mukurumbira wayo uri mukuchena kwayo isingaenzaniswi kune rumwe rutivi, uye kuoma uye kushomeka kwekubviswa kwayo kune rimwe.Chimiro cheGlycyrrhiza glabra ndicho chitubu cheGlabridin, asi Glabridin inongoverengera 0.1% -0.3% yezvese zvirimo, kureva kuti, 1000kg yeGlycyrrhiza glabra inogona kungowana 100g yeGlabridin, 1g yeGlabridin yakaenzana ne1g yegoridhe remuviri.
Hikarigandine inomiririra inomiririra yemishonga yemishonga, uye kuchena kwayo kunowanikwa neJapan
Glycyrrhiza glabra chirimwa cherudzi rweGlycyrrhiza.China ndiyo nyika ine zviwanikwa zvemishonga zvakapfuma pasi rose, uye kune marudzi anopfuura mazana mashanu emakwenzi anoshandiswa mumakiriniki, pakati pawo anonyanya kushandiswa licorice.Zvinoenderana nenhamba, mwero wekushandiswa kwe licorice unodarika 79%.
Nekuda kwenhoroondo refu yekushandiswa, inoperekedzwa nemukurumbira wepamusoro, chiyero chetsvakiridzo pamusoro pekukosha kwe licorice haina kungoputsa kuburikidza nemiganhu yenzvimbo, asiwo kushandiswa kwakawedzerwa.Maererano netsvagiridzo, vatengi muAsia, kunyanya muJapan, vane ruremekedzo rukuru rwezvizoro zvine mishonga yemishonga.114 herbal cosmetic ingredients yakanyorwa mu "Japan's General Cosmetics Raw Materials", uye kwatove nemhando mazana maviri ezvizoro zvine mishonga yemishonga muJapan.
Iyo inozivikanwa kuve ine super whitening mhedzisiro, asi ndeapi matambudziko mukushandisa inoshanda?
Iyo hydrophobic chikamu che licorice inobvisa ine akasiyana e flavonoids.Sechikamu chikuru cheiyo hydrophobic chikamu, halo-glycyrrhizidine ine inhibitory mhedzisiro pakugadzirwa kwe melanin uye inewo anti-inflammatory uye anti-oxidant mhedzisiro.
Mamwe data ekuyedza anoratidza kuti kuchena kwechiedza cheGlabridin chakakwira zvakapetwa ka232 pane yevhitamini C yakajairwa, yakapetwa ka16 kupfuura iyo yehydroquinone, uye 1,164 yakakwira kupfuura iyo arbutin.Panzira yekuwana yakasimba chena basa, mwenje Glabridin inopa nzira nhatu dzakasiyana.
1. Kudziviswa kwebasa re tyrosinase
The main whitening mechanism ofGlabridinndeyekudzivisa kuumbwa kwe melanin nemakwikwi inhibiting tyrosinase chiitiko, kutora chikamu che tyrosinase kubva kune catalytic ring ye melanin synthesis uye kudzivirira kusungwa kwe substrate kune tyrosinase.
2. Antioxidant effect
Inogona kumisa zvese tyrosinase uye dopa pigment kuchinjana uye kuita kwe dihydroxyindole carboxylic acid oxidase.
Yakave yakaratidzwa kuti pamusangano we 0.1mg / ml, photoglycyrrhizidine inogona kuita cytochrome P450 / NADOH oxidation system uye scavenge 67% yemahara radicals, ane simba rakasimba re antioxidant.
3.Inhibit zvinhu zvinoputika uye kurwisana neUV
Parizvino, tsvakurudzo shoma yakataurwa pamusoro pekushandiswa kwe photoglycyrrhizidine mukudzidza kweUV-induced skin photoaging.Muna 2021, mune imwe chinyorwa mujenari repakati Journal of Microbiology uye Biotechnology, photoglycyrrhizidine liposomes yakadzidzwa kuitira kugona kwavo kunatsiridza UV chiedza-induced erythema uye chirwere cheganda nekudzivisa kuzvimba zvinhu.Photoglycyrrhizidine liposomes inogona kushandiswa kuvandudza bioavailability ine shoma cytotoxicity pamwe nani melanin inhibition, zvinobudirira kuderedza kutaura kweanopisa cytokines, interleukin 6 uye interleukin 10. Naizvozvo, inogona kushandiswa senge topical therapeutic agent kurwisa UV radiation-induced kukuvara kweganda. nekudzivisa kuzvimba, izvo zvinogona kupa mamwe mazano ekutsvagisa kwechiedza chezuva chekuchenesa zvigadzirwa zvekudzivirira.
Muchidimbu, kuchena kwekuita kwe photoglycyrrhizidine kunozivikanwa, asi hunhu hwayo hunenge husina kunyungudika mumvura, saka inonyanya kudiwa pakugadzirwa nekugadzira nzira mukushandiswa kwekuwedzera kweganda rekuchengetedza chigadzirwa, uye parizvino iri mhinduro yakanaka kuburikidza ne liposome. encapsulation tekinoroji.Uyezve, mufananidzoGlabridinliposomes inogona kudzivirira UV-induced photoaging, asi basa iri rinoda mamwe makiriniki ekuedzwa kuti asimbiswe uye mashandisirwo ekutsvaga aitwe.
Zvigadzirwa zvekuchengetedza ganda zvine mufananidzoGlabridin muchimiro chechinhu chinosanganisa.
Nepo pasina kupokana kuti photoGlabridine ine yakanaka kwazvo yekuchena mhedzisiro, iyo yakabikwa mutengo inorambidzwa zvakare nekuda kwekuomerwa mukubvisa uye zvirimo.Mucosmetic R&D, basa rekudzora mitengo rakabatana zvakananga kune zvetekinoroji uye maitiro esainzi.Nokudaro, inzira yakanaka yekudzora mari yekugadzira uye kuwana hutano hwakachengeteka uye hunobudirira nekusarudza zvinhu zvinoshanda uye kuzvibatanidza mukubatanidza ne photoglycyrrhizidine.Pamusoro peiyo padanho reR&D, kumwe kuongorora kunodiwa maererano nekutsvagisa kwephotoglycyrrhizidine liposomes uye nzira dzekupedzisira dzekubvisa.
Nguva yekutumira: Aug-30-2022